Monday, January 14, 2013

The next step in Life science/medicine!



Biology, like any other stream of modern science has seen great discoveries leading to mind-blowing inventions and a better understanding of disease, disease progression and ‘life’ in general. Great discoveries starting from the discovery of penicillin (in 1928 but actual use started in the 1940s) to advances in stem cells research led to a renaissance in the field of medicine. However, the current technologies and the drug discovery paradigm still leave a lot to be desired in terms of understanding the biology of the healthy and the diseased! So what is missing?

The basic understanding of the life processes has improved and different approaches both “top-down” and “Bottoms-up” viewpoints are being looked into. We have moved ahead with great advances in the hardware side wherein we can now observe single cell in action; we can sequence the whole genome/transcriptome of humans, yet I believe that we are not there where we should have been. What is missing is a holistic approach to understanding the healthy and the diseased. A collaborative effort looking at the broader picture is the need of the hour. Authors like Dr Amit Goswami (Book- The Quantum Doctor) has argued in the favour of an approach that takes into consideration not only the different branches of biology but also includes various aspects of quantum physics and alternate medicine to better understand and deal with disease. This is not a farfetched idea and is doable. Various well reputed thinkers/writers like Dr Roger Penrose, Dr Deepak Chopra have opined that the current thought process of considering the human body and the cellular processes therein as mechanistic sans consciousness is fraught with naivety and therefore a paradigm shift is probably needed!

So what is going to be the next “Eureka” moment in the field of Life sciences? Probably, a holistic approach to understanding life and disease!