ok folks, so now we would be discussing some basics and pathology of type 2 diabetes
Well, to start with let us understand what happens in the disease. We all know that in type 2 diabetes, the body's ability to utilize glucose with the aid of insulin goes down dramatically!!
This is sometimes called as "insulin resistance" which is a precursor to the full blown type 2 diabetes. When this condition sets its foot our humble pancreas start to pump more insulin to let the glucose seep in to the various tissues especially muscles and adipose. Interestingly, in diabetics another disastrous event takes place. The 'great' liver has this property of producing glucose, the process is known as "gluconeogenesis". This process normally occurs when the body perceives a need for glucose and probably when it is in the starving mode! however even though there is enough glucose flowing in the system of diabetics the liver starts producing glucose and releases it in the blood thus raising its level further!!!
So as we can see there are multiple problems here and everything is leading to increase in blood sugar!!!! At the same same time research has shown that there is an increase in fatty acid level as well in the system (triglycerides etc.). This increase in sugar and fatty acids has a detrimental effect on the pancreas. We have seen and it is also known that such an insult to the pancreas leads to the death of beta cells (chief insulin producing cells)
So folks as one can see the key to avoid or delay the progression of the disease is to 'somehow' do away with insulin resistance! and as mentioned in my previous blog nothing is as effective as exercise or yoga.
Both Yoga and exercise have been shown to increase glucose uptake and there is a view based on research that exercise activates a pathway called AMPK (5' AMP-activated protein kinase) which incidentally has been shown to be activated by a class of widely used drug for treating this disease called metformin!
In all, it is suffice to say that to be diabetes free it is imperative to have physical activity on a daily basis!
Well, to start with let us understand what happens in the disease. We all know that in type 2 diabetes, the body's ability to utilize glucose with the aid of insulin goes down dramatically!!
This is sometimes called as "insulin resistance" which is a precursor to the full blown type 2 diabetes. When this condition sets its foot our humble pancreas start to pump more insulin to let the glucose seep in to the various tissues especially muscles and adipose. Interestingly, in diabetics another disastrous event takes place. The 'great' liver has this property of producing glucose, the process is known as "gluconeogenesis". This process normally occurs when the body perceives a need for glucose and probably when it is in the starving mode! however even though there is enough glucose flowing in the system of diabetics the liver starts producing glucose and releases it in the blood thus raising its level further!!!
So as we can see there are multiple problems here and everything is leading to increase in blood sugar!!!! At the same same time research has shown that there is an increase in fatty acid level as well in the system (triglycerides etc.). This increase in sugar and fatty acids has a detrimental effect on the pancreas. We have seen and it is also known that such an insult to the pancreas leads to the death of beta cells (chief insulin producing cells)
So folks as one can see the key to avoid or delay the progression of the disease is to 'somehow' do away with insulin resistance! and as mentioned in my previous blog nothing is as effective as exercise or yoga.
Both Yoga and exercise have been shown to increase glucose uptake and there is a view based on research that exercise activates a pathway called AMPK (5' AMP-activated protein kinase) which incidentally has been shown to be activated by a class of widely used drug for treating this disease called metformin!
In all, it is suffice to say that to be diabetes free it is imperative to have physical activity on a daily basis!
Absolutely sir.exactly what we had worked on.
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